"Oral Bacteria Are More Active Than You Think! The Surprising Role of Oral Bacteria in Cancer"
Your mouth is not just about teeth and gums; it has the second largest and diverse microbiota after the gut, hosting more than 700...
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Salem Lab
Advancing Head and Neck Oncobiome Research
Our Latest Research News
Our Research and Impact
Bacterial-Derived Vesicles and Toxins in Oncogenesis
We investigate the dynamic interplay between oral bacteria and cancer cells in head and neck cancers. Our research focuses on understanding the mechanistic effects of bacterial-derived vesicles and toxins on crucial tumorigenic events associated with carcinogenesis.
Novel Therapeutic and Prognostic Targets in Cancer
We assess the clinical utility of bacterial-derived extracellular vesicles and certain potent inflammatory molecules as potential therapeutic agents in cancer. Our team has uncovered important findings and established effective international collaboration.
Utilizing In Vitro, Ex Vivo and In Vivo Research Assays
We employ multiple in vitro, ex vivo and in vivo assays, including the CRISPR/Cas9 technology, to investigate the different aspects of head and neck carcinogenesis such as phenotypic switching, invasion, metastasis, apoptosis, and drug resistance.
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