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Welcome to Salem Lab
(Head & Neck Oncobiome Group)

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@ University of Helsinki
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Advancing Head and Neck Oncobiome Research

Our Latest Research News

Our Research and Impact

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Bacterial-Derived Vesicles and Toxins in Oncogenesis

We investigate the dynamic interplay between oral bacteria and cancer cells in head and neck cancers. Our research focuses on understanding the mechanistic effects of bacterial-derived vesicles and toxins on crucial tumorigenic events associated with carcinogenesis.

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Novel Therapeutic and Prognostic Targets in Cancer

We assess the clinical utility of bacterial-derived extracellular vesicles and certain potent inflammatory molecules as potential therapeutic agents in cancer. Our team has uncovered important findings and established effective international collaboration.

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Utilizing In Vitro, Ex Vivo and In Vivo Research Assays

We employ multiple in vitro, ex vivo and in vivo assays, including the CRISPR/Cas9 technology, to investigate the different aspects of head and neck carcinogenesis such as phenotypic switching, invasion, metastasis, apoptosis, and drug resistance.

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